Thousands of documented clinical successes through the contemporary re-discovery of established science

CLINICAL SCIENCE

Close to 80 million of adult Americans are struggling to maintain a healthy weight. Obesity affects not only life style but is also associated with up to 4x the risk of certain cancers2, 1.5x risk of stroke2,3, and 3x risk of death4. Make your fast step towards a healthier weight with the KetoMedicalTM program.

The human body: the brain, the bones, and the muscles are designed to run on sugar. When calories are plentiful and carbohydrates are in abundance, the excess sugar (glucose) in the blood is stored as fat. When both calories and carbohydrates become scarce, the body uses these fat reserves to feed itself with help of the natural chemicals produce by the liver, known as ketones5,6. The presence of ketone bodies in the blood (ketosis) supresses hunger through a variety complex biochemical mechanism - just another adaptation that helped our ancestors survive through long periods of deprivation5,6.

While very low-calorie, low-carbohydrate diets provide fast results in significant weight loss, it may potentially lead to the breakdown of muscle tissue. In the 1960’s and 70’s the revolutionary work of Blackburn and colleagues has demonstrated that the appropriate supply of dietary protein during ketogenic fasting may minimize the loss of muscle mass while still providing effective weight loss7,8. Proper medical supervision, the type and the quality of the protein utilized during very-low calorie, low-carbohydrate diet are highly important to ensure safety of the approach9,10.

The KetoMedicalTM program is based on the principles established by Blackburn et al and 40 years of subsequent research in protein metabolism and clinical weight loss11,12. Three unique features separate KetoMedicalTM from other medically-supervised weight-loss programs:

  • The meal replacement compound is fat-free – alleviating concerns about additional cardiovascular risk due to potential elevation of cholesterol and lipids levers observed in high-fat ketogenic diets13
  • The meal replacement compound is carbohydrate-free – ensuring faster transition into low blood sugar state and hunger suppressive effect of ketosis5,6
  • The very low caloric content of the program makes it possible to limit the active meal-replacement to 10 days only, making compliance easier versus longer-term interventions14

The KetoMedicalTM meal replacement compound is based on high quality whey protein isolate with patented15 mixture of essential ammino-acids, intended to maximize lipolisis (fat burning), preserve lean body mass, and suppress hunger16-19.

Long-term success in weight loss requires commitment to lifestyle change, including healthy diet and exercise. Bariatric surgery has been proven an effective tool towards weight loss in the selected patients, but often requires a pre-procedural weight loss in order to qualify for insurance reimbursement. Pre-procedural weight loss improves surgical outcomes in both bariatric20,21 and other abdominal procedures, urological surgeries22. Whatever the goals and circumstances, KetoMedicalTM program should be considered as the fast, first step towards a meaningful weight loss and a long-term healthy life.

Consult your physician to discuss your weight loss goals,details of the program, and your eligibility.

References:

  • 1. C.Ogden et al, NCHS Data Brief; Number 131, October 2013
  • 2. D.Guh et al, BMC Public Health 2009, 9:88
  • 3. HP.Strazzulo et al, Stroke 2010; 41: e418-26
  • 4. D.Guh et al, BMC Public Health 2009, 9:886HP. Strazzulo et al, Stroke 2010; 41: e418-26
  • 5. A.Paoli et al, J. Environ. Res. Public Health 2014; 11:2092-2107
  • 6. R.Veech, Prostaglandins, Leukotrienes and Essential Fatty Acids 70 (2004) 309–319
  • 7. Blackburn, G.L., Bistrian, B.R., Flatt, J.P., and Sizer, J.:Role of a protein sparing modified fast in a comprehensive weight reduction program. In Recent Advances in Obesity Research: I,Howard, Alan, Ed. London, Newman Publishing Ltd., 1975.
  • 8. B.Bistrian et al, Diabetes 25:494-504
  • 9. S.Phinney et al, Arch Intern Med 1983;143:2258-2261
  • 10. T.Waden et al, Annals of Internal Medicine. 1983 ; 99 : 675 - 684
  • 11. G.Cappello et al, Nutrition & Metabolism 2012, 9:96
  • 12. G.Castaldo et al, International Journal of Endocrinology Volume 2015, Article ID 72373
  • 13. J.Volek and E. Westman, Cleve Clin J Med 2002; 69: 849-62
  • 14. H.Leidy et al , Am J Clin Nutr 2015;101(Suppl):1320S–9S
  • 15. European Patent # EP2276358B1 ; http://www.google.com.ar/patents/EP2276358B1?cl=en
  • 16. A.Hector et al, JJ Nutr 2015;145:246–52.
  • 17. M.Westerterp-Plantenga et al, British Journal of Nutrition (2012), 108, S105–S112
  • 18. S.Pal et al, Obesity Reviews (2013) 14, 324–343
  • 19. M.Balage et al, Current Opinion in Clinical Nutrition andMetabolic Care 2010, 13:265–270
  • 20. P.Gerber et al, Scand J Surg 2014; 104: 33-9
  • 21. PD.Edholm et al, OBES SURG (2011) 21:345–350
  • 22. S.Williams et al, Clin Genitourin Cancer; epub Dec 2014
  • 23. J.Anderson et al, Postgrad Med 2011;123: 205-13 and http://www.hmrprogram.com/
  • 24. T.Wadden et al, Am J Clin Nutr 2004; 80: 560-8 and https://www.optifast.com/Pages/index.aspx